Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.


Widely hand-me-down diabetes drugs have exceptional effects on men's and women's hearts, a imaginative study suggests. Researchers examined how three commonly prescribed treatments for type 2 diabetes seized 78 patients who were divided into three groups. One group took metformin alone, the in the second place group took metformin plus rosiglitazone (sold under the trade name name Avandia) and the third group took metformin plus Lovaza, a type of fish oil natural. Metformin reduces blood sugar opus by the liver and improves insulin sensitivity.



Rosiglitazone also improves insulin irritability and moves free fatty acids out of the blood. Lovaza lowers blood levels of another kidney of fat called triglycerides. The researchers found that the drugs had very sundry and sometimes opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders skin clear. The investigation appears in the December issue of the American Journal of Physiology - Heart and Circulatory Physiology.



Although metformin had glaring heart effects in women, it caused the ticker metabolism of men to burn less sugar and more fats. Chronic burning of fat by the nitty-gritty results in harmful changes that can lead to heart failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making stomach metabolism more normal in men, metformin unsurpassed made it worse, looking even more like a diabetic heart," study elder author Dr Robert Gropler said in a university news release.



And "But in women, metformin had the desired accomplish - lowering fat metabolism and increasing glucose perceptiveness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to reduce some of the negative heart belongings of metformin alone in men. Taking rosiglitazone in addition to metformin further improved women's fundamentals metabolism, compared to taking metformin alone.



The addition of Lovaza to metformin did not have a strong effect either situation for men or women, the researchers said. "Our study suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The deliberate over did not, however, be shown a cause-and-effect link between the drug combinations and soul changes akumentis endothik-es tab. It showed only an association.

tag : metformin women heart rosiglitazone diabetes blood metabolism lovaza researchers

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