Dysfunction Of The Autonomic Nervous System May Be A Marker Of Later Development Of Certain Types Of Kidney Disease

Dysfunction Of The Autonomic Nervous System May Be A Marker Of Later Development Of Certain Types Of Kidney Disease.


A person's nature dead beat may suggest insight into their future kidney health, a renewed study suggests article source. A high resting heart rate and low beat-to-beat determination rate variability were noted in study patients with an increased risk for kidney disease, according to a bang released online July 8 in advance of publication in an upcoming print issue of the Journal of the American Society of Nephrology.



The declaration suggests that dysfunction of the autonomic nervous system - which regulates uncontrolled body functions such as heart rate, blood pressure, temperature and stress reply - may be a marker for late development of certain types of kidney disease, explained Dr Daniel Brotman of Johns Hopkins University School of Medicine and colleagues, in a rumour hand out from the American Society of Nephrology check this out. Previous studies have suggested a link between autonomic nervous process dysfunction (dysautonomia) and chronic kidney disease and its progression.



Brotman's team analyzed heart and kidney information from 13241 US adults, aged 45 to 64, enrolled in a long-term lucubrate of atherosclerosis risk. In general, a low resting heart rate and greater beat-to-beat variability in essence rate indicate a healthy autonomic nervous system and good cardiovascular health.



The researchers found that nation with a high resting heart rate had a twofold increased hazard of developing kidney failure years later, and those with a lower beat-to-beat variability in heart bawl out had a 1,5-times increased risk. Brotman and colleagues noted that this does not prove a cause-and-effect relationship, but they speculated that problems in the autonomic flappable system may damage blood vessels in and around the kidneys.



So "We craving our findings will encourage further research to better define the putative role of the autonomic nervous system in precipitating and exacerbating renal kidney affliction in humans," the authors wrote check this out. "This, in turn, may in the end lead to novel therapeutic approaches once the mechanisms for our findings are better characterized".

tag : kidney autonomic heart system nervous disease resting increased variability

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