Non-Invasive Diagnosis Of Traumatic Dementia At An Early Stage

Non-Invasive Diagnosis Of Traumatic Dementia At An Early Stage.


A "virtual biopsy" may lend a hand interpret a degenerative brain disorder that can occur in maestro athletes and others who suffer repeated blows to the head, says a new study. Symptoms of long-lived traumatic encephalopathy (CTE) can include memory problems, impulsive and erratic behavior, indentation and, eventually, dementia article source. The condition, which is marked by an accumulation of abnormal proteins in the brain, can only be diagnosed by an autopsy.



But a specialized imaging tack called magnetic resonance spectroscopy (MRS) may tender a noninvasive way to diagnose CTE at an early stage so that treatment can begin before further perception damage occurs, say US researchers. MRS - sometimes referred to as "virtual biopsy" - uses authoritative magnetic field and radio waves to gather news about chemical compounds in the body more information. The researchers used MRS to examine five retired licensed male football players, wrestlers and boxers, ages 32 to 55, with suspected CTE and compared them to a dominance group of five age-matched men.



Compared to the control group, the brains of the one-time athletes had increased levels of choline, a cell membrane nutrient that signals the bearing of damaged tissue, and of glutamate/glutamine (Glx). The former athletes also had altered levels of gamma-aminobutyric acid (GABA), aspartate, and glutamate.



An estimated 3,8 million concussions reciprocal to sports and diversion occur in the United States each year, according to the Centers for Disease Control and Prevention. The think over was to be presented Dec 1, 2010 at the annual meeting of the Radiological Society of North America in Chicago.



So "By help us identify the neurochemicals that may play a role in CTE, this swotting has contributed to our understanding of the pathophysiology of the disorder," Alexander P Lin, a principal investigator at the Center for Clinical Spectroscopy at Brigham and Women's Hospital in Boston, said in a sorority news release. "Being able to pinpoint CTE could help athletes of all ages and levels, as well as war veterans who diminish mild brain injuries, many of which go undetected" more. Because the study is being presented at a medical meeting, its observations and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

tag : athletes levels brain group compared researchers control meeting presented

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