Vitamin E Fights Against Diseases

Vitamin E Fights Against Diseases.


There might be some best news in the bear against Alzheimer's disease: A new study suggests that a large daily dose of vitamin E might relieve slow progression of the memory-robbing illness. Alzheimer's patients given a "pharmacological" dispense of vitamin E experienced slower declines in thinking and memory and required less caregiver set than those taking a placebo, said Dr Maurice Dysken, lead author of a new study published Dec 31, 2013 in the Journal of the American Medical Association resource. "We found vitamin E significantly slowed the rebuke of sequence versus placebo," said Dysken, who is with the Geriatric Research Education and Clinical Center of the Minneapolis VA Health Care System.



Experts stressed, however, that vitamin E does not seem to dispute the underlying cause of Alzheimer's and is in no advance a cure. The study involved more than 600 patients at 14 VA medical centers with peaceable to moderate Alzheimer's. Researchers broken the group into quarters, with each receiving a different therapy for men. One-quarter received a daily dose of 2000 global units (IU) of alpha tocopherol, a form of vitamin E That's a less large dose; by comparison, a daily multivitamin contains only about 100 IUs of vitamin E.



The other sets of patients were given the Alzheimer's medication memantine, a combine of vitamin E and memantine, or a placebo. People who took vitamin E unattended experienced a 19 percent reduction in their annual percentage of decline compared to a placebo during the study's average 2,3 years of follow-up, the researchers said. In realistic terms, this means the vitamin E group enjoyed a more than six-month lacuna in the progression of Alzheimer's, the researchers said.



This delay could mean a lot to patients, the researchers said, noting that the deteriorate experienced by the placebo group could translate into the complete loss of the ability to dress or bathe independently. The researchers also found that kinsmen in the vitamin E group needed about two fewer hours of woe each day. Neither memantine nor the combination of vitamin E plus memantine showed clinical benefits in this trial. Therapy with vitamin E also appears to be safe, with no increased danger of bug or death, the researchers found.



The annual death rate was 7,3 percent for community in the vitamin E group and 9,4 percent for those on placebo. People should keep in mind, however, that vitamin E entranced at such large doses can have an effect on other medications, said Heather Snyder, pilot of medical and scientific operations for the Alzheimer's Association. "We know there might be some interactions with other medications that plebeians might be taking, including blood thinners or cholesterol medications".



That means that people who want to take vitamin E to act toward Alzheimer's should do so under the supervision of their doctor. Snyder said the findings are "certainly definitive enough to warrant further research," but she'd like to see the study replicated with another set of patients. The patients in this inquiry were nearly all male, so were not wholly representative of the general public.



Research also needs to be done to figure out why vitamin E helps Alzheimer's patients. At this point, no one is steadfast how it helps slow mental decline. The vitamin E in use in the study is a fat-soluble antioxidant, but "we don't have a cogent theory why that attribute should be positive in patients with Alzheimer's disease".



However, such research into treating Alzheimer's might not be as potentially healthful as studies that focus on preventing the disease altogether, Dr Denis Evans, of Rush University Medical Center in Chicago, wrote in an op-ed article that accompanied the study. "This is an distinguished trial, and it points out the limitations of finding ways to treat the disease. It's a reasonable tiff for putting more emphasis on prevention article source. If you look at all trials of Alzheimer's disease, of which this is an example of one of the best, the care effects are real but they are also relatively small and they focus only on the symptoms of the disease".

tag : vitamin alzheimer patients study placebo researchers disease group memantine

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Dr. Alejandra Falto

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