Body Weight Affects Kidney Disease

Body Weight Affects Kidney Disease.


Obesity increases the hazard of developing kidney disease, a fresh study suggests. Moreover, declines in kidney function can be detected covet before people develop other obesity-related diseases such as diabetes and high blood pressure, the researchers said in Dec, 2013. The researchers analyzed figures collected from nearly 3000 iniquitous and white young adults who had normal kidney function read this. The participants, who had an average length of existence of 35, were grouped according to four ranges of body-mass index (BMI), a measurement of body fat based on level and weight.



The groups were normal weight, overweight, obese and extremely obese. Over time, kidney act as decreased in all the participants, but the decline was much greater and quicker in overweight and fleshy people, and appeared to be linked solely with body-mass index weightloss. "When we accounted for diabetes, loaded blood pressure and inflammatory processes, body-mass index was still a predictor of kidney function decline," research first author Dr Vanessa Grubbs, an assistant adjunct professor of drug at the University of California, San Francisco, said in a university news release.



So "There was something lone about just being too large that in and of itself affected kidney function even before the onset of kidney disease. "We're not able to bedevil out the reason for that just yet, but we're hoping to look at it in a future study". The researchers also found that measuring blood levels of a protein called cystatin C is better than the more stock method of measuring creatinine levels in detecting casuistic changes in kidney function.



This holds true even when kidney changes are still within what is considered the reasonable range. "The fact that we were able to use this marker to see declines in kidney purpose long before patients would be deemed to have chronic kidney disease is good, in that it may allow us to detect problems earlier and all being well intervene sooner. The findings, published online recently in the American Journal of Kidney Diseases, show the constraint for doctors to intervene early to prevent kidney plague in obese patients, the researchers said.



And "We're getting larger and larger at younger and younger ages, so the problems we will foresee that are directly related to obesity are going to become more common, and they're going to wince earlier in life. "Even before the level at which we can diagnose illnesses, decline in kidney function is happening. Is it reversible? We're not sure. Preventable? It stands to apology that it would be side effect. Although the analyse showed an association between obesity and increased risk of kidney disease, it did not prove a cause-and-effect relationship.

tag : kidney function disease obesity researchers weight decline blood obese

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