Alzheimer's Disease Is Associated With A High Blood Pressure

Alzheimer's Disease Is Associated With A High Blood Pressure.

People affliction from cardiovascular virus who have lower-than-normal blood pressure may face a higher jeopardize of brain atrophy - the death of brain cells or connections between brain cells, Dutch researchers crack June 2013. Such brain atrophy can lead to Alzheimer's complaint or dementia in these patients i found it. In contrast, similar patients with high blood pressure can measurable brain atrophy by lowering their blood pressure, the researchers added.

Blood pressure is measured using two readings. The peak number, called systolic pressure, gauges the pressure of blood stirring through arteries. The bottom number, called diastolic pressure, measures the pressure in the arteries between heartbeats herbal. Normal blood on for adults is less than 120/80, according to the US National Heart, Lung, and Blood Institute.

For the study, 70 to 90 was considered usual diastolic blood pressure, while under 70 was considered low. "Our evidence might suggest that patients with cardiovascular disease represent a subgroup within the undetailed population in whom low diastolic blood pressure might be harmful," said researcher Dr Majon Muller, an epidemiologist and geriatrician at VU University Medical Center in Amsterdam.

On the other hand, lowering blood require in nation with high blood pressure might slow brain atrophy. "Our findings could denote that blood pressure lowering is beneficial in patients with higher blood force levels, but one should be cautious with further blood pressure lowering in patients who already have low diastolic blood pressure".

The gunshot was published in the June 10 online edition of JAMA Neurology. A US first-rate noted the complex effects of blood pressure levels on the brain. "High blood turn the heat on has been shown to increase the risk of vascular brain lesions and brain atrophy. Trials of blood prevail upon lowering in patients with hypertension have shown reduced risk of brain lesions," said Dr Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association.

However, in patients with hypertension, the relation between the levels of systolic and diastolic blood influence and mastermind atrophy has been less clear. This new study suggests that low diastolic blood tension levels were associated with brain atrophy regardless of blood pressure levels after patients developed dementia. "These findings suggest that while curing and control of high blood bring pressure to bear is very important for brain and cardiovascular health, caution is needed in patients who have low diastolic blood intimidation levels".

To see what changes blood pressure would make in the progression of brain atrophy, Muller's assort studied 663 patients who suffered from heart disease, cardiovascular disease, circumferential artery disease or abdominal aortic aneurysm. The average age of participants was 57 and most were men. People whose diastolic blood demand was below 70 had more brain atrophy over time, the boning up found.

For people with higher-than-normal blood pressure, brain atrophy decreased when their blood apply pressure did. When blood pressure rose, however, atrophy increased. Another expert, Dr Sam Gandy, ally director of the Mount Sinai Alzheimer's Disease Research Center in New York City, said that the verdict "is an important cautionary tale".

This implies that one must accustom the approach to the individual patient. Correction of hypertension is helpful, but reducing blood lean on in patients with normal blood pressure is risky and complicated" go here. Although the go into found an association between low diastolic blood pressure and the risk of developing brain atrophy for rank and file with artery disease, it did not establish a cause-and-effect relationship.

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