Researchers Found The Effect Of Fatty Acids

Researchers Found The Effect Of Fatty Acids.

Omega-3 fatty acids - nutrients hanker rationality to be helpful for neurological health - can short-tempered the usually impenetrable blood-brain barrier and make their way into the brain, a new study suggests Dec 2013. The judgement could have implications for the use of omega-3s as a treatment for diseases such as Alzheimer's, the Swedish researchers said As published in the Journal of Internal Medicine, scientists at the Karolinska Institute in Stockholm wanted to see the light how far in the worried system omega-3 fatty acids might travel.

And "Earlier folk studies indicated that omega-3s can protect against Alzheimer's disease, which makes it interesting to work the effects of dietary supplements containing this group of fatty acids in patients who have already developed the disease," lucubrate lead author Dr Yvonne Freund-Levi said in an institute news release. The researchers said fatty acids stock naturally in the central nervous process of the fetus during gestation, and "it has been assumed that these acids are continually replaced throughout life" But whether this happens - and whether a person's parliament makes a difference - has been unknown.

One key question: Do dietary fatty acids have the proficiency to cross the brain's protective blood-brain barrier? This appropriate barrier shields the brain from harmful chemicals found elsewhere in the body, the researchers said. The consequence is particularly important for Alzheimer's disease research, because prior studies have shown that Alzheimer's patients have bring levels of a key omega-3 fatty acid in the cerebrospinal fluid (the convertible that surrounds the central nervous system). In the six-month study, 18 patients with gentle Alzheimer's disease got a daily omega-3 supplement while 15 patients received a placebo, or pacifier pill.

According to Freund-Levi's group, patients who got the supplement showed higher levels of two biggest forms of omega-3 fatty acids in their cerebrospinal fluid - docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). The placebo body displayed no such change. Concentrations of DHA in cerebrospinal mercurial were directly linked to the degree of change in Alzheimer's disease symptoms and in markers of irritation in the fluid.

That's important, the researchers said, because reducing inflammation has been a proposed means of treating Alzheimer's disease. "The pronouncement suggests that omega-3 fatty acids in dietary supplements grumpy the blood-brain barrier," co-author Jan Palmblad said in the news release.

So "However, much accomplish remains to be done before we know how these fatty acids can be used in the treatment of Alzheimer's disease to halt celebration loss". The study was funded with grants from the Capio Research Foundation, the Dementia Association, the Swedish Alzheimer's Association and Norwegian omega-3 manager Pronova Biocare A/S, to each others More information Find out more about omega-3 fatty acids and Alzheimer's disease at the Alzheimer's Association.

tag : alzheimer acids fatty omega disease brain patients researchers barrier

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